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Cureus 2022;14(10):e30787

We discovered that TAX6/Calcineurin serves as a key component in inhibiting GPCR signaling: while tax6 mutants were unable to generate pulsatile activity and reach exact adaptation in response to the natural stimulus diacetyl (Figs 3 and 4), their calcium dynamics following optogenetic activation was similar to wt worms (Fig 5)

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Baseline microbiome and metabolome are associated with response to ITIS diet in an exploratory trial in patients with rheumatoid arthritis