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For the exhaustion criteria, four subjects (15.4%) with exhaustion in the L-carnitine group changed to normal, while only one subject (4.2%) in the placebo group changed to normal in exhaustion criteria

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Methionine and vitamin B12 are critical cofactors in the homocysteine-to-methionine cycle, which produces S-adenosylmethionine (SAMe), the universal methyl donor in over 200 enzymatic reactions including phosphatidylcholine synthesis

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