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If you're not eating enough, this calorie deficit can lead to fatigue and sluggishness, especially if your body hasn't yet adjusted to this lower intake
Safety and tolerability While both medications share common side effects, such as gastrointestinal issues, and constipation
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These are fundamentally different approaches with different regulatory standards, evidentiary requirements, and expected outcome profiles
^Based on a 6-month clinical trial (n=180) of individuals who were enrolled between FebruaryApril 2024, with overweight or obesity taking semaglutide or tirzepatide for weight loss and related outcomes through the WW Clinic Program and participating in the GLP-1 companion nutrition program
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