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(2000) Evaluation of low-dose endotoxin administration during pregnancy as a model of preeclampsia
Lets see how: In the foetus: heart disease, and intrauterine growth restriction Newborns: poor feeding, microcephaly (smaller than usual head size), and encephalopathy Infants: poor feeding, slow growth, and neurologic complications Toddlers: poor growth, progression of microcephaly, encephalopathy, megaloblastic anemia, developmental delays, and seizures Adolescents and adults: neurologic and psychiatric illness, cognitive decline, abnormal clot formation, spinal cord degeneration
The inhibition of somatostatin by DSIP has been found by a separate study, thus leading to the speculation that this peptide might have larger and more universal functions regarding human physiology than just primary sleep promotion, for which the direct inhibitory effects of somatostatin are more than peculiar
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Its unique mechanism of action ensures it remains a staple in regenerative medicine
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