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Effect of Epitalon and melatonin on lifespan and spontaneous carcinogenesis in senescence-accelerated mice

Takeda et al crossed Alzheimer transgenic mice (APP23) with two types of diabetic mice (ob/ob and NSY mice) and found a significant increase in IL-6 in the brains of hybrid mice fed with a high-fat diet

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The acidic pH these products require may destabilize the copper-peptide bond, and the exfoliating action may remove copper peptides from the skin before they can be absorbed