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It's generally advised against in individuals with a personal or family history of medullary thyroid carcinoma or in those with Multiple Endocrine Neoplasia syndrome type 2

Retatrutide's known side effect profile from trials includes nausea, vomiting, diarrhoea, decreased appetite, and injection-site reactions effects consistent with other GLP-1-based therapies

Wu et al., 2018)

While many patients report softer, more hydrated skin within 1 to 2 weeks after their first session, structural changes like pore tightening and elasticity improvement build progressively

Clinical trials have shown that weekly doses of semaglutide can result in up to 10 percent weight loss within months, and 19 percent within six months

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