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The fact that folinic acid, even at high dose, did not change metabolic markers of methylation and/or glutathione metabolism unless it was combined with mB12 is an important finding as it has direct implication for treatment of inter-related but distinct metabolic disorders associated with ASD
It is synthesized by bacteria and serves as a biomethylation compound of certain heavy metals
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HSPA9, also known as mortalin, is primarily responsible for the maintenance of mitochondrial proteostasis (Kaul et al., 2002
Many research powders are kept refrigerated or frozen until use
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