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Individuals with ARTHS present with developmental delay, cognitive impairment (100% penetrance), delay or absence of speech (100%), facial dysmorphism (85%), feeding difficulties (78%), and neonatal hypotonia (76%) in a study of 76 individuals with KAT6A mutations (Kennedy et al, 2019)

Theres also the thorny matter of lifelong dependence: Most patients who stop taking the drugs regain the weight theyd lost

WOSINSKA: There's just too much money

Acrolein exerts its toxic effects through inhalation, ingestion and dermal exposure

Tracy LE, Minasian RA, Caterson EJ

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