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doi: 10.1186/s12886-019-1116-z 107 DonachiePHJBarnesBLOlaitanMSparrowJMBuchanJC
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He reports that most vegans show adequate B12 levels to make clinical deficiency unlikely, but they may show restricted activity of B12-related enzymes, leading to elevated homocysteine levels, which has been linked to increased risk of heart disease and stroke
These effects usually diminish as your body adjusts
That said: human data remains limited, sample sizes are small, and no studies have directly compared direct glutathione supplementation against precursor approaches on meaningful clinical endpoints
From there, your cells use B12 to support energy metabolism, specifically by helping convert carbohydrates and fats into usable fuel
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