Genetic testing: In certain instances, genetic testing can identify inherited conditions that affect Vitamin B12 metabolism
These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
7 In this cohort of women, the prevalence of IC/BPS symptoms was 2.3%
However, the effect was significantly smaller than what has been observed with FDA-approved versions, which can produce up to 15% weight loss in a year
However, some doctors also say they are hearing about mood flattening from people on the medication
In fact, many healthcare providers now prescribe them to individuals without diabetes who meet specific criteria for weight management