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GLP-1 increases preingestive satiation via hypothalamic circuits in mice and humans
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However, clinical consideration is still required
It is commonly prescribed for adults with type 2 diabetes and may also help some patients lose weight as part of its effect on appetite, digestion, and blood sugar regulation
The consequence is muscle loss
Additionally, semaglutide may increase insulin sensitivity and reduce cravings for high-calorie foods, amplifying weight loss when paired with modest dietary changes
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