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This timing aligns with the medication's mechanism: semaglutide immediately begins slowing gastric transit, which your stomach interprets as an unfamiliar sensation before adaptation occurs
So thats why we do know it is a safe drug actually. A BMI of 30 or higher qualifies on its own
However, limited representation of lean MASH and certain ethnic groups (e.g., Black patients) constrains generalizability to those subpopulations, an issue shared by many MASH trials [1]
meta-analysis: OR = 0.72, 95% CI [0.610.86]), anxiety disorders (FinnGen: OR = 0.81, 95% CI [0.760.87]
*J Physiol Paris.* 95(1-6):315-24
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