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It could point to several things: A different cause: your fatigue might stem from thyroid problems, iron deficiency, or sleep apnea rather than B12

[23] [24] Intracellular vitamin B 12 is maintained in two active coenzymes, methylcobalamin and adenosylcobalamin

B12 is water-soluble, so the body clears what it does not use

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What to look for in a certificate of analysis Every reputable supplier provides a Certificate of Analysis (COA) with each batch