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Skin biopsy with IENFD counting provides the gold standard for small fiber neuropathy assessment

Although short-term trials show minimal adverse effects, the prolonged intake of agents such as selenium, vitamin D, and zinc can lead to toxicity if not monitored adequately 58

LPS activates Toll-like receptors (TLRs), particularly TLR4, 72 triggering immune responses and cytokine release

Complications of vitamin B12 or folate deficiency anaemia Although it's uncommon, vitamin B12 or folate deficiency (with or without anaemia) can lead to complications, particularly if you have been deficient in vitamin B12 or folate for some time

It is a supportive tool alongside a plan, not a replacement for one

10.1200/JCO.19.01203 J Clin Oncol