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Unlike the SURMOUNT-1 trial, the patients were followed for only 40 weeks with a significant reduction in glycosylated haemoglobin (A1C) so that an A1C drop of more than 2% was seen with all three doses of tirzepatide as compared to semaglutide, which showed a drop of 1.86%

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Peppard PE, Young T, Barnet JH, et al