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Patients have reported loss of coverage for the medication, which has led them to experience weight gain
Three consecutive proline residues at positions 3 through 5, plus two more at positions 8 and 11, give the molecule a constrained backbone and account for its reported resistance to enzymatic degradation in acidic media
This side effect is relieved by splitting the recommended feeding rate into twice daily doses
For further discussion of these and other risks and uncertainties that could cause actual results to differ from Lilly's expectations, see Lilly's Form 10-K and Form 10-Q filings with the Trademarks and Trade Names All trademarks or trade names referred to in this press release are the property of the company, or, to the extent trademarks or trade names belonging to other companies are referenced in this press release, the property of their respective owners
It is also important to consider that obesity itself the primary condition retatrutide is being developed to treat is strongly associated with poor sleep quality, obstructive sleep apnoea (OSA), and insomnia
London Group Meeting, December 2007
