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Among the 8 identified metabolites, the levels of L-acetylcarnitine, L-carnitine, ribonic acid, and glucaric acid tended to increase from stage 1 and became significantly higher in stage 3 when compared to controls (Fig

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Duration of gradual systemic effect on an average individual Fair to medium brown Complexion 1-3 Months Dark Brown Complexion 1-6 Months Very dark Complexion 6-12 months Black Complexion 12-24 months 2

Disclaimer: This information reflects findings from preclinical and observational research

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