Conjugation of indolic ITCs with glutathione in the biosynthesis of indole-sulfur phytoalexins and in PEN2-mediated indole GSL hydrolysis has been reported recently 35,81
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In the skin, it inhibits an enzyme called tyrosinase, a key component for melanin production, the pigment that gives skin its color
It binds plasma proteins more tightly and is retained far longer, which is why a single dose holds therapeutic levels for roughly eight to twelve weeks and supports a maintenance interval of two to three months
Alpha Arbutin evens the skin tone
Chua, Xingshun Xu, Zhigang Miao Neurochemical Research.2017