bimagrumab glp-1 New Developments in Pharmacological Treatment of Obesity and Type 2 Diabetes—Beyond and within Receptor Agonists From Fat Burn to Muscle

Source: Jastreboff et al., NEJM 2022 (SURMOUNT-1)

Study measures Demographics Demographic data, such as age, height and weight (to calculate BMI), gender, race, education and ethnicity were assessed by a demographics questionnaire

Rapid injection (entire dose delivered in 2mL, which exceed the deltoid muscle's comfortable absorption capacity

hCG can also be used to help restore spermatogenesis in men hypogonadal hypogonadism or steroid-induced impairment of spermatogenesis

Hot or cold therapy : Some individuals find relief by applying heat pads or cold compresses to the affected legs

The exact reasons dual agonism produces greater weight loss are still being studied