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This activation potentially promotes the translocation of GLUT4, a major glucose transporter, to the cell surface, thus facilitating glucose entry into cells

In a small study, semaglutide reduced insulin needs in people with type 1 diabetes: after 3 months, participants no longer required mealtime insulin, and after 6 months, 7 of 10 no longer needed any basal insulin

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In reproductive tissues, this translates to more rapid repair following an injury or surgery and stronger architecture in the endometrium or tunica

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion