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This alteration of the microbiota may partly explain the variability in GLP-1RA responsiveness and presents opportunities for combination therapy using probiotics or prebiotics to augment therapeutic effectiveness
Yes, severe diarrhea leads to dehydration if fluids are not replaced
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However, stronger doesnt mean right for everyone. Individual responses vary significantly, and semaglutide produces clinically meaningful results for the majority of patients who take it
Future clinical studies should determine which patient groups should be targeted as potential candidates for the symptomatic and/or neuroprotective effects of GLP-1RAs, to find out, whether combinations of GLP-1RA with other classes of drugs can further enhance their effectiveness, and evaluate their long-term effect on the course of the disease and side effects
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