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Excess histamine can cause severe inflammation and a wide variety of symptoms

Association between serum thymosin 4 levels of rheumatoid arthritis patients and disease activity and response to therapy

124: 20715 Clarke L, Waxman DJ

However, what you tend to feel immediately upon injection is firmness due to swelling and inflammation (think of how a newly-bruised area will feel like a firm bump)

Although supplementation did not significantly increase serum 25-hydroxyvitamin D concentrations, it attenuated the seasonal decline in vitamin D status, suggesting a protective effect during periods of low sunlight exposure

However, some people can experience minor digestive upset, cramps, or constipation, and if you find this to be the case, consume your iron supplement with your first meal of the day during your feeding window