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NNMT is highly expressed in adipose tissue and plays a role in cellular methyldonor economy and nicotinamide processing

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These are similar to vitamin B12, but theyre not bioavailable and so will not improve your intake of the vitamin

The authors also point out that in some rare genetic disorders of B12 metabolism, the active forms may be required, and that smokers, who tend to have an excess of thiocyanate in their blood, may benefit from a taking a form other than cyano-B12

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