I recommend: at least 2,000 mcg (g) cyanocobalamin once each week, ideally as a chewable, sublingual, or liquid supplement taken on an empty stomach or at least 50 mcg daily of supplemental cyanocobalamin or a serving of B12-fortified foods three times a day, each containing at least 190 percent of the Daily Value listed on the nutrition facts label Those over 65 years of age should take at least 1,000 mcg (g) cyanocobalamin every day
Common approaches include: Morning dosing supports daytime recovery and activity Evening or bedtime injection aligns with natural repair processes during sleep Post-workout administration enhances recovery immediately after training stress Some users report that late-day injections cause sleep disruption, possibly related to nitric oxide system activation
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Andrs E, Zulfiqar AA, Vogel T QJM : monthly journal of the Association of Physicians 2020
Alcoholism: Clinical and Experimental Research, 33 (9), 1489- 1507.
Taking too much of certain vitamins and other supplements can be harmful, so its best to work with a healthcare professional