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The combination itself has not been validated in controlled human trials
AOD-9604 is a modified fragment of human growth hormone consisting of residues 177 to 191 with a tyrosine added at the amino terminus
It does this without affecting any other enzyme or part of the metabolic cycle (Neelakantan, 2018)
So we dont have that same sort of rigour, if you like, on just overall safety. The third safety question is legal, and the answer differs by jurisdiction: United States
Tighe MP, Cummings JR, Afzal NA
For a compound to gain FDA approval, it must go through extensive, multi-phase clinical trials in humans to prove both safety and efficacy for a specific condition
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