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PMID: 34324435
Owing to their similar properties to the natural extracellular matrix (ECM) (high water content, porous structure, and biocompatibility) 14 , hydrogel scaffolds have been widely investigated in tissue engineering, in which injectable hydrogels with the potential for minimally invasive surgery and facile stem cells and drug loading capacities have been verified to have a positive effect on the stimulation of cartilage regeneration 15,16
It promotes dendritic spine formation and increases synaptic connectivity in preclinical models of neural development
Memory loss or confusion
Newsome PN, Ambery P
Mechanism: FOXO4-DRI (or Proxofim) is a designer peptide that interrupts the FOXO4-p53 binding loop responsible for cellular senescence
