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They are often sold as research use only, and the FDA has flagged Ipamorelin (and other peptides) as presenting safety risks when compounded without sufficient evidence
doi:10.2147/DDDT.S365416 Medical Citation URL
The FDA determined the tirzepatide shortage resolved in late 2024 and the semaglutide shortage resolved in February 2025, and it set enforcement deadlines through 2025 for compounders to wind down shortage-based production
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