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class IIa A recommendation) already taking sodiumglucose cotransporter 2 inhibitors, without differentiating between HF phenotypes
Lozano, A.M
Moreover, considering that carnitine metabolism produces TMAO, which has been recently recognized as a novel risk factor for cardiovascular diseases, the use of uncontrolled amounts of carnitine as dietary supplements must be carefully reviewed. "Since carnitine is often used by athletes with no clear understanding of its effects and risks, it becomes critical to provide information about the characteristics of this compound and its probable harmful effects on health," the researchers said
Kim Na-young, Hanmis senior managing director, said the company would use the new trial to build evidence for patients whose metabolic diseases often overlap
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That changed in 2025 with the publication of SURMOUNT-5, the first randomized head-to-head trial, published in the New England Journal of Medicine
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