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The drugs active ingredient, semaglutide, binds itself to the receptors of a hormone which controls blood sugar, stimulating the release of insulin when glucose levels are high
People who attend at least 60% of sessions and complete the programme lose an average of 3.6 kg and reduce HbA1c by 2.1 mmol/mol
This could be interpreted as alarming and signaling that we should lengthen NPO times, particularly in diabetic patients who may have undiagnosed gastroparesis, or it could potentially be seen as reassuring, indicating that maybe a low volume of gastric contents isnt as big of a risk factor for aspiration as once thought.1 The authors of this paper recommend that patients be fasted from solid food for 24 hours
PMID 12908852
10.1038/ijo.2014.153 83
