The pleiotropic effects of GLP-1R agonists and SGLT2 inhibitors have been extensively investigated
Wegovy highlights of prescribing information, Novo Nordisk (2024) The risk of depression, anxiety, and suicidal behavior in patients with obesity on glucagon-like peptide-1 receptor agonist therapy, Scientific Reports (2024) Decreased risk of anxiety in diabetic patients receiving glucagon-like peptide-1 receptor agonist: A nationwide, population-based cohort study, Frontiers in Pharmacology (2022) Most GLP-1 medications correlated with a lower likelihood of anxiety and depression diagnoses, Epic Research (2024) Dopamine release in the midbrain promotes anxiety, Biological Psychology (2021) Dopamine primes the brain for enhanced vigilance, MIT News (2018) Why your cardiologist may prescribe semaglutide (Wegovy), Yale Medicine (2024) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
Treating these underlying causes can also help and one way to do that is by undergoing therapy for these mental health issues
NICE Technology Appraisal (TA875) on semaglutide for weight management specifies that within the NHS, Wegovy should be prescribed by specialist weight management services and used for a maximum of 2 years
Here's what to expect
In an open letter in June, the company emphasized that it is the "only lawful supplier of FDA-approved tirzepatide medicines" and that products from other unverified sources may be "fake, counterfeit, or otherwise unsafe products." "(Safety) is our number one priority, and this is a great way for patients to know they're getting genuine Lilly medicine," said Rhonda Pacheco, group vice president for Lilly U.S