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Contact your GP or seek immediate medical help if you experience: Severe or persistent abdominal pain (potential pancreatitis) Right upper quadrant pain or jaundice (potential gallbladder disease) Chest pain, severe palpitations, or difficulty breathing Signs of dehydration from vomiting or diarrhoea Significant mood changes, suicidal thoughts, or severe anxiety Symptoms of hypoglycaemia (if diabetic) Rapid or excessive weight loss Treatment goals and alternatives should be discussed