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Animals were 10 weeks of age on arrival, and were fed a standard laboratory swine diet, formulated for balanced nutrition and growth (#8753, composed of 16% protein, 33% carbohydrates, and 3.9% fat for a total of 2.3 kcal/g, Envigo, Indianapolis, IA) during a one-week acclimation period

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The RESTORE randomized trial (N=230) demonstrated that leukocyte-rich PRP improved pain and function scores in knee osteoarthritis compared to saline at 12 months 20

We also explored whether this association varied across different symptom profiles

The evidence is overwhelming that nearly everyone can benet from becoming more physically active