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10.1021/bi701559f 95 ShenP.HanL.ChenG.ChengZ.LiuQ
Higher doses should be taken with caution, as they may increase the risk of side effects such as gastrointestinal discomfort or a fishy body odor
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Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal, further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly (for parenteral supplementation) or daily (for oral supplementation)
They reduce appetite
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