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Global impacts of western diet and its effects on metabolism and health: A narrative review
97 In conclusion, SIRT1 maintains lipid metabolic balance by inhibiting lipid synthesis and promoting fatty acid oxidation through the regulation of key transcriptional regulators such as SREBP-1c and PGC-1, along with enzymes involved in hepatic lipid metabolism
The compound was developed by the Australian biotech firm Metabolic Pharmaceuticals as a research tool to isolate the lipolytic signaling domain of growth hormone without the receptor-binding region responsible for its anabolic and glucose-handling effects
References Johansen PB, Segev Y, Landau D, et al
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