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These findings establish a critical role for GSH in promoting Rickettsia cell division and pathogenesis, contributing to the concept that GSH plays multifaceted roles in the fitness of intracellular pathogens

That distinction between suppression and modulation is critical and represents one of the key advantages peptides may offer over conventional immunosuppressive therapies

AEDG is the most extensively characterised of this family in the contemporary international literature

J Exp Med 192:10011014 Kehrer JP (2000) The Haber-Weiss reaction and mechanisms of toxicity

Acts as the body's master antioxidant