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Berberine side effects are predominantly gastrointestinal and may include: Diarrhoea, constipation, or abdominal discomfort Nausea and flatulence Cramping or bloating These effects are typically dose-dependent and may be minimised by starting with lower doses and taking berberine with meals

doi: 10.3389/fendo.2018.00035

Ryu JK, Kim SJ, Rah SH et al (2017) Reconstruction of LPS transfer cascade reveals structural determinants within LBP, CD14, and TLR4-MD2 for efficient LPS recognition and transfer

The region where the patient is located is also important because the diet of people in different regions is not consistent

Healing & Injury Repair Accelerate tissue repair and reduce inflammation