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The close ECD-TMD interaction in the apo-state is reminiscent of the state in the recent structure of the smoothened receptor, which shows extensive interactions of its ECD with the ECLs of its TMD [45]
The human body naturally makes a hormone called GLP-1, or Glucagon-Like Peptide-1
Comparison of the Long-Term Effects of Liraglutide and Glimepiride Monotherapy on Bone Mineral Density in Patients with Type 2 Diabetes
doi:10.1016/j.taap.2011.12.018 [7] Marques AC, Mariana M, Cairrao E
10.1210/jc.2013-2538 24
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