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In Dialysis Patients Patients with kidney disease undergoing dialysis often have anemia with deformed red blood cells

In the nucleus, HIF-1 drives the up-regulation of glycolysis gene transcription

ESPEN 37 (2020) 923

It helps regulate the immune response, enhances the activity of immune cells, and promotes the production of cytokines, which are small signaling molecules that regulate immune responses

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For instance, individuals with undiagnosed sleep apnea may find that their quality of sleep is compromised, leading to daytime fatigue