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Chem Eur J 10:46644672 Cho CJ et al (2025) Diacylation of peptides enables the construction of functional vesicles for drug-carrying liposomes
dose-dependent GI adverse events (nausea, vomiting) similar to other amylin analogues Exposure: Dose-proportional increases in Cmax and AUC Gastric Effects: Dose-dependent slowing of gastric emptying confirmed via paracetamol absorption test Appetite Suppression: Reduced ad libitum food intake at doses 1.2 mg Clinical Significance: Established feasibility of once-weekly dosing and identified dose range for Phase 2 studies
B 117 , 84908501 (2013)
Transl Res
Expression of class Pi glutathione transferase in human malignant melanoma cells
