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One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12

"A lot of these studies are based on animal models," he said

You experience symptoms of deficiency

This alters the cells epigenetic methylation potential, influencing histone and DNA methylation states that regulate gene expression for adipogenesis and metabolism

Vitamin D is fat-soluble and can accumulate to toxic levels, causing nausea, weakness, and kidney damage

Supplementing B-12 through injections provides a rapid, bioavailable dose directly into the bloodstream