Although not a significant function of the PPP, it can operate to metabolize dietary pentose sugars derived from the digestion of nucleic acids as well as to rearrange the carbon skeletons of dietary carbohydrates into glycolytic and /or gluconeogenic intermediates
In vitro research has demonstrated that hCG decreases TIMP-1 secretion in endometrial stromal cells, thereby facilitating extravillous trophoblast invasion with MMP-2 levels increasing and gelatine zymography confirming increased MMP-2 activity following hCG treatment
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doi: 10.1186/1471-2377-11-62 67 BuchwaldDHerrellRAshtonSBelcourtMSchmalingKSullivanPet al
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