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AOD9604 is the subject of active experiments
Mechanisms include modulation of profibrotic signaling pathways (e.g., TGF-/Smad, ANG II-mediated cascades), inhibition of profibrogenic gene expression, reduction of collagen deposition, and induction of apoptosis in activated stellate cells
\DNA Repair: NAD+ is crucial for enzymes that help repair damaged DNA, supporting genetic stability
Government of Canada
This project was an extremely complex project with many challenging aspects and a tight schedule
PMID 33296025 - half-life and pharmacology
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