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2a), which is consistent with the previously reported high thermal stability of other GRXs 14,31
Fibrillar structures were also observed, but they were not associated with copper ions, suggesting that copper promotes the formation of toxic oligomers that disrupt membranes ( Impaired autophagy plays an important role in IAPP toxicity, due to the accumulation of excessive amounts of IAPP oligomers intracellularly
Kolarz, M., Gowacki, R., Stompr, T., Wyrolak, J
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