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Amino acid modifications in the N-terminus and at certain positions in the C-terminus are involved in the resistance to DPP-4 inhibition, thus prolonging its half-life

Blood cells were removed by centrifugation at 2 000 g for 20 min and plasma from animals of each group was pooled

Folic acid can worsen depression, agitation, insomnia or obsessive thinking in some susceptible patients

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