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However, women should not take L-carnitine supplements during pregnancy or while breastfeeding without consulting with a healthcare provider due to the lack of safety data [8]

In the present study, data were obtained from literature mining, and the rates of body weight change from the initial values were selected as the therapeutic index

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This framework also reinforces why supplements aimed at histamine regulation are best viewed as adjunctive support , not alternative therapy, alongside appropriate medical care

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