Serious reactions are extremely rare, especially when injections are performed by licensed medical professionals
Liposomal delivery protects fragile nutrients like glutathione from stomach acid, allowing them to be absorbed directly into the cells
For women specifically, hormonal factors add another layer cycle-driven water retention, perimenopause, and cortisol sensitivity can all mask fat loss on the scale even when the deficit is real
The Bottom Line: How Long Do You Stay on Semaglutide For Weight Loss Most people stay on semaglutide for 6 to 12 months, but the right duration depends on your body, your goals, and how your weight responds over time
Kasliwal RR, Bansal M, Gupta R, et al
Yes, you might need to change your diet if you plateau