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p=0.02) ( Figure S3 )
The mechanistic case is coherent and supported by what we know about each modality separately
Murken 1 , D
Some complications improve with appropriate treatment, but others, such as problems with the nervous system, can sometimes be permanent
Currently, those with alcohol and substance use disorders (ASUDs) receive behavioural, motivational, and cognitive treatment, but the number of approved medications is somewhat limited
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