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Upon synthesizing global research findings, experts reached a consensus to exclude lower urinary tract infections as a symptom or diagnostic criterion for IC/PBS (Hanno and Dmochowski, 2009)
Data are presented as box and whisker plots showing the mean value (central marker) and the minimum-maximum range of values (whiskers)
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Boosting NAD + via the de novo pathway through Trp supplementation is not as popular, as quinolinic acid generated from Trp conversion is neurotoxic, and kynurenines have immunomodulatory roles 58
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