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169,177,178 In a preliminary trial in 17 healthy reproductive-aged women, taking 4,000 mg of an omega-3 fatty acid supplement (providing 1,860 mg eicosapentaenoic acid [EPA] and 1,500 mg docosahexaenoic acid [DHA]) daily for one month led to reductions in levels of FSH, a hormonal marker of diminished ovarian reserve and early menopause, in normal weight, but not obese, participants
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SASP (senescence-associated secretory phenotype) results revealed that FOXO4-DRI downregulates the levels of IL-1 , IL-6 , IL-8 , and TNF- (Figure 4H)
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A meta-analysis of 10 studies with 419 total participants found that gymnema supplementation significantly reduces fasting blood glucose, postprandial blood glucose, and HbA1c compared to baseline
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