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The most recent and methodologically rigorous of them, restricted to four placebo-controlled trials in 667 patients, found no significant difference from placebo on MDS-UPDRS Part III in either the on- or off-medication state [7]
Things to Consider: Its important to remember a few things: Results can vary
Most of the clinical benefits observed in studies occurred after 2 to 4 weeks of daily use, with results improving further over 8 to 16 weeks
Insulin resistance with poor glycemic control
Simoni M, Brigante G, Rochira V, Santi D, Casarini L
Diarrhea, which is less common, often develops lateraround weeks 2 to 3as your gut adjusts
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